This research develops science teaching materials based on concepts by using a group investigation model on human respiratory system material. This study discusses the procedures for conducting research and development following development research according to the Directorate General of Higher Education (2008) by combining the stages of the learning model according to Dick and Carrey (1990). The study was conducted at Public Junior High School 3 in Ternate City in class VIIIb with a total of 20 students. Research samples taken from participants with normal distribution with a significant value> 0.05 were tested with the help of SPSS software. The results showed the development of science teaching materials based on the concept is very well used as a learning medium in science learning with the results of the research percentage of 97% in terms of media and 97.4% in terms of material that has been validated by experts as media experts and material experts. Student learning outcomes data is implemented using the t test with the help of SPSS software. For testing hypotheses, the pre-test and post-test data of the experimental class were analyzed using paired sample t-test (different test of two paired samples). In this study, the difference between the pre-test and post-test of each meeting and the difference between the post-test and post-test of each meeting. Evidenced by student learning outcomes in the post-test without the product with the post-test using the product the significant value is 0.00 <0.05. The importance of differences in learning outcomes are significant. Likewise with student learning outcomes, improving material on the human respiratory system reaches 90.59. Increased student learning outcomes are marked by student learning completeness that reaches 100%. This proves that the development of science teaching materials based on the concept of maps using the group investigation model is very well used as a learning medium so that it can improve student learning outcomes in human respiratory system material Public Junior High School 3 in Ternate City.