The present research is an attempt of using Inquiry Learning Approach in Understanding Science. To study the effectiveness of Inquiry Learning Approach in context to achievement of F.Y. B.Sc. Students. The hypothesis of the study was ‘There will be no significant difference between the mean achievement scores of Pre-test and Post-test’. The study was experimental in nature. The Single Group Pre-test Post-test design was used. The population of the study comprised of F.Y. B.Sc. students of Sardar Patel University. The sample of the present study comprised of 100 F.Y. B.Sc. students of J & J Patel Science College, Nadiad. The sample was selected using convenient sampling technique. The tools used to collect the data were Achievement Test and Reaction Scale. The data was analyzed using t – test. The major findings of the study reveal that understanding Science using Inquiry Learning Approach was found to be effective after the intervention programme.